Coronavirus Disease 2019 (COVID-19) is an infectious disease which is caused by a new strain of coronavirus. Older individuals and people with comorbidities have a higher risk to develop more severe illness. COVID-19 survivors will have active immunity in conjunction with increase of SARS-CoV-2 antibody (Ab) titer 2-weeks after the symptoms onset and will be lasted until 12-weeks. Therefore, it will give protection against reinfection of COVID-19. This study reports a case of COVID-19 rapid reinfection in sixty-year-old man with diabetes mellitus. Case illustration: a sixty-year-old man presented to the emergency department with fever accompanied by cough, runny nose, malaise, and metallic taste since one day before admission to hospital. There was a history of uncontrolled diabetes mellitus (DM) and COVID-19 infection 35-days before hospital admission without any symptoms. The current physical examinations demonstrated a mild dyspnea with oxygen saturation 97%, and diffuse rhonchi at the right area of chest auscultation. Chest X-ray discovered a multiple consolidation of the right lung, with suspicion of viral pneumonia. Fasting blood glucose (FBG) was 205 mg/dl, and 2-hour postprandial glucose was 508 mg/dl. The polymerase chain reaction (PCR) of SARS-CoV-2 via nasopharyngeal swab was taken and the result was positive. COVID-19 Ab titers IgM and IgG were 0.18 U/ml and 0.43 U/ml (<0.8 U/ml → non-reactive), respectively. The patient was diagnosed with COVID-19 reinfection and DM. The patient was treated with convalescent plasma, antivirus, antibiotics, insulin, steroid, anticoagulant, and other symptomatic medications. As the results, a well improvement of his clinical condition and the increase of Ab COVID-19 IgM and IgG evaluation test after convalescent plasma administration, 0.28 AU/ml and 17.67 AU/ml, respectively, were recorded. Summary: Researches revealed that DM might cause the specific immunity system dysfunction and the low production of antibody. This study found that poor blood-glucose control with a low Ab of SARS-CoV-2 production might induce this patient to have a COVID-19 reinfection. Advance immunological study about the correlation between DM and COVID-19 is very essential in the management of COVID-19 patients with DM.
| Published in | American Journal of Internal Medicine (Volume 10, Issue 2) |
| DOI | 10.11648/j.ajim.20221002.11 |
| Page(s) | 20-27 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Coronavirus, COVID-19 Reinfection, Diabetes Mellitus, Antibody, Antibody Titer
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APA Style
Albert William Hotomo, Heri Sutrisno Prijopranoto. (2022). COVID-19 Reinfection in 60-Year-Old Man with Diabetes Mellitus, East Nusa Tenggara, Indonesia: A Case Report. American Journal of Internal Medicine, 10(2), 20-27. https://doi.org/10.11648/j.ajim.20221002.11
ACS Style
Albert William Hotomo; Heri Sutrisno Prijopranoto. COVID-19 Reinfection in 60-Year-Old Man with Diabetes Mellitus, East Nusa Tenggara, Indonesia: A Case Report. Am. J. Intern. Med. 2022, 10(2), 20-27. doi: 10.11648/j.ajim.20221002.11
AMA Style
Albert William Hotomo, Heri Sutrisno Prijopranoto. COVID-19 Reinfection in 60-Year-Old Man with Diabetes Mellitus, East Nusa Tenggara, Indonesia: A Case Report. Am J Intern Med. 2022;10(2):20-27. doi: 10.11648/j.ajim.20221002.11
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Download@article{10.11648/j.ajim.20221002.11,
author = {Albert William Hotomo and Heri Sutrisno Prijopranoto},
title = {COVID-19 Reinfection in 60-Year-Old Man with Diabetes Mellitus, East Nusa Tenggara, Indonesia: A Case Report},
journal = {American Journal of Internal Medicine},
volume = {10},
number = {2},
pages = {20-27},
doi = {10.11648/j.ajim.20221002.11},
url = {https://doi.org/10.11648/j.ajim.20221002.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20221002.11},
abstract = {Coronavirus Disease 2019 (COVID-19) is an infectious disease which is caused by a new strain of coronavirus. Older individuals and people with comorbidities have a higher risk to develop more severe illness. COVID-19 survivors will have active immunity in conjunction with increase of SARS-CoV-2 antibody (Ab) titer 2-weeks after the symptoms onset and will be lasted until 12-weeks. Therefore, it will give protection against reinfection of COVID-19. This study reports a case of COVID-19 rapid reinfection in sixty-year-old man with diabetes mellitus. Case illustration: a sixty-year-old man presented to the emergency department with fever accompanied by cough, runny nose, malaise, and metallic taste since one day before admission to hospital. There was a history of uncontrolled diabetes mellitus (DM) and COVID-19 infection 35-days before hospital admission without any symptoms. The current physical examinations demonstrated a mild dyspnea with oxygen saturation 97%, and diffuse rhonchi at the right area of chest auscultation. Chest X-ray discovered a multiple consolidation of the right lung, with suspicion of viral pneumonia. Fasting blood glucose (FBG) was 205 mg/dl, and 2-hour postprandial glucose was 508 mg/dl. The polymerase chain reaction (PCR) of SARS-CoV-2 via nasopharyngeal swab was taken and the result was positive. COVID-19 Ab titers IgM and IgG were 0.18 U/ml and 0.43 U/ml (Summary: Researches revealed that DM might cause the specific immunity system dysfunction and the low production of antibody. This study found that poor blood-glucose control with a low Ab of SARS-CoV-2 production might induce this patient to have a COVID-19 reinfection. Advance immunological study about the correlation between DM and COVID-19 is very essential in the management of COVID-19 patients with DM.},
year = {2022}
}
TY - JOUR T1 - COVID-19 Reinfection in 60-Year-Old Man with Diabetes Mellitus, East Nusa Tenggara, Indonesia: A Case Report AU - Albert William Hotomo AU - Heri Sutrisno Prijopranoto Y1 - 2022/03/03 PY - 2022 N1 - https://doi.org/10.11648/j.ajim.20221002.11 DO - 10.11648/j.ajim.20221002.11 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 20 EP - 27 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20221002.11 AB - Coronavirus Disease 2019 (COVID-19) is an infectious disease which is caused by a new strain of coronavirus. Older individuals and people with comorbidities have a higher risk to develop more severe illness. COVID-19 survivors will have active immunity in conjunction with increase of SARS-CoV-2 antibody (Ab) titer 2-weeks after the symptoms onset and will be lasted until 12-weeks. Therefore, it will give protection against reinfection of COVID-19. This study reports a case of COVID-19 rapid reinfection in sixty-year-old man with diabetes mellitus. Case illustration: a sixty-year-old man presented to the emergency department with fever accompanied by cough, runny nose, malaise, and metallic taste since one day before admission to hospital. There was a history of uncontrolled diabetes mellitus (DM) and COVID-19 infection 35-days before hospital admission without any symptoms. The current physical examinations demonstrated a mild dyspnea with oxygen saturation 97%, and diffuse rhonchi at the right area of chest auscultation. Chest X-ray discovered a multiple consolidation of the right lung, with suspicion of viral pneumonia. Fasting blood glucose (FBG) was 205 mg/dl, and 2-hour postprandial glucose was 508 mg/dl. The polymerase chain reaction (PCR) of SARS-CoV-2 via nasopharyngeal swab was taken and the result was positive. COVID-19 Ab titers IgM and IgG were 0.18 U/ml and 0.43 U/ml (Summary: Researches revealed that DM might cause the specific immunity system dysfunction and the low production of antibody. This study found that poor blood-glucose control with a low Ab of SARS-CoV-2 production might induce this patient to have a COVID-19 reinfection. Advance immunological study about the correlation between DM and COVID-19 is very essential in the management of COVID-19 patients with DM. VL - 10 IS - 2 ER -
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